Scorpion Venom Antiserum
(Lyophilised, Polyvalent, Enzyme refined Equine immunoglobulins)
Description
Polyvalent anti-scorpion venom serum is prepared from the purified plasma of healthy horses, which have been hyperimmunized against venom of the most dangerous scorpions mentioned below. The antivenin is purified by pepsin degestion, controlled heating and precipitation by caprylic acid followed by sterilization
Composition:
Each 1 ml serum contains antibodies that neutralize the following venoms :
Leiurus quinquestraitus 50LD50
Androctonus ameoreuxi 35LD50
Paraspecifically:
Androctonus crassicauda
Androctonus aeneas
Androctonus australis
Scorpiomarus palmatus
Bathus occitanus
Ortho-Cresol (preservative) 0.25%
Protein 17%
Clinical Pharmacology:
Venom from a single scorpion may contain several neurotoxins such as histamine, serotonin and enzymes. The most important clinical effects of envenomation are neuromuscular, neuroautonomic or local tissue effects.
Grades of Clinical Picture Serverity:
Grade 0 : No Local or Systemic Signs.
Grade I : Local Signs, pain, and / or parathesia at the site of string.
Grade II: Local Signs and pain + remote pain and / or parathesia.
Grade III: Local pain + cranical, autonomic or somatic neuromuscular dysfunction.
Indications:
Treatment of envenomation from the stings of the scorpion species mentioned in composition.